“Lodo Therapeutics Corporation, a drug discovery and development company focused on identifying and producing unique, bioactive natural products directly from the microbial DNA sequence information contained in soil, today announced that it has formed a strategic drug discovery collaboration with Genentech, a member of the Roche Group.
Under the terms of the agreement, Genentech will utilize Lodo Therapeutics’ proprietary genome mining and biosynthetic cluster assembly platform to identify novel molecules with therapeutic potential against multiple disease-related targets of interest to Genentech. Lodo will receive an undisclosed upfront payment and is eligible to receive research, development and commercialization milestone payments up to $969 million based on achievement of certain predetermined milestones. In addition, Lodo is eligible to receive tiered-royalties on sales of certain products resulting from the collaboration.
From Business Insider:
“Maria Gotsch, president and CEO of Partnership Fund for New York City, who’s been working to promote the biotech scene in New York for the past 15 years, sees other challenges for the city apart from real estate, including a lack of a biotech ecosystem like you might see in Cambridge’s Kendall Square and dearth of seed funding for early-stage companies.
The shortage of space for biotechs in New York, Gotsch said, is a relatively recent occurrence. Until recently, weren’t even enough biotech companies who chose to remain in the city with most founders choosing to relocate to the West Coast. “They weren’t even starting here,” she said.”
“Although the costs of bringing the Long Island Railroad into Grand Central Station have escalated to $11.2 billion, the East Side Access project will create economic development benefits for the city and region that exceed $18 billion. Using methodology developed by Boston Consulting Group for a study published by the Partnership for New York City in 2004, we can project that East Side Access will generate economic development benefits at least 1.61 times its cost. The project will significantly enhance utilization and access to the midtown transit hub, resulting in new development, increased employment and expanded commercial activity in the city and, potentially, in Long Island as well. There are also clear transportation benefits of the project, which will increase the capacity of the LIRR and reduce commuting time for thousands of passengers. Reform of MTA procurement and contracting procedures is certainly necessary to reduce construction costs of major projects—and the MTA has already demonstrated a commitment to begin this process. But it is clear that the value generated by investments in transit are enormous and need to be factored into any cost-benefit analysis, said Kathryn Wylde, President & CEO of the Partnership for New York City.
Celent, a global research and advisory firm for the financial services industry, recently announced that DBS digibank won their prestigious Model Bank award for Best Digital Bank. DBS Bank was recognized for its partnership with Partnership Fund portfolio company Kasisto and its KAI platform, which resulted in the most comprehensive, forward-thinking deployment of conversational AI in the finance industry.
Mayor Bill de Blasio today announced a first-of-its-kind targeted loan program that will make more than $5 million in affordable capital accessible to women entrepreneurs seeking to grow their businesses. WE Fund: Growth is designed to overcome barriers faced by women seeking to grow their businesses.
Partnership Fund portfolio company New York Business Development Corporation is partnering with the City of New York to help disperse loans between $25,000 and $125,000.
The following testimony was submitted on behalf of Kathryn Wylde, President & CEO of the Partnership for New York City.
Thank you Chair Espinal and members of the committee for the opportunity to testify on Int. 723, sponsored by the Speaker. The Partnership for New York City represents the city’s business leaders and largest private sector employers working to enhance the economy of the five boroughs of New York City and maintain the city’s position as the pre-eminent global center of commerce, innovation and economic opportunity.
The Partnership recognizes the important contributions of the tourism industry to New York City. At the same time, we question the economic value of sightseeing buses, specifically in Manhattan south of 60th Street, during the business week. In December, 2017, the Partnership released a study of the cost of traffic congestion that identified $20 billion a year in economic losses and costs due to congestion that is largely generated by traffic to and from the central business districts of Manhattan. While our study did not quantify the extent to which tour buses contribute to the congestion problem, there is ample anecdotal evidence that their negative impact is substantial. Moreover, there is no credible, independent study that has determined that tour buses are a net contributor to the city economy.
The Manhattan central business districts should be off-limits to tour buses since the streets do not have capacity to handle them. There is inadequate curbside space and nowhere for these buses to park on weekdays, from 7 a.m. to 7 p.m. There are plenty of alternative means of transportation for visitors seeking to move around Manhattan, including MTA transit, new ferry and bike services, as well as taxies, liveries and for-hire vehicles.
Conditions in Manhattan streets are not suited to sightseeing bus activity. The average speed of vehicular travel in the central business district is only 6.8 miles per hour – a situation that gets worse every year. The sidewalks that buses use for passenger waiting, loading and unloading are equally as congested as the streets.
There are serious safety and air quality concerns associated with sightseeing buses, which regularly stop at unauthorized locations and are often seen idling at the curb. The common practice of “stacking” buses at popular sites takes up multiple lanes on overcrowded streets. These problems are most acute in neighborhoods with a confluence of tourist attractions, a high density of people and vehicles, and narrow streets and sidewalks. Int. 723 is a first step toward assessment of the value of the tour bus industry, hopefully paving the way for stricter regulation of its activity. If passed, it would require the Department of Transportation (DOT) to authorize where buses can stop. DOT would be empowered to collect bus location data to help with these decisions and could attach conditions to the authorization of stops. Violations could be grounds for license revocation.
Governor Cuomo’s Fix NYC panel, which recommended better traffic management and congestion pricing, specifically identified the need to study the negative contribution of tour buses to the high cost of traffic congestion. We suggest such a study be undertaken and that, in the interim, there be a reduction of authorized buses navigating Manhattan south of 60th Street during weekday business hours. The Partnership looks forward to working with the Council on this issue.
Digital Reasoning, a leader in Artificial Intelligence (AI) that understands human intentions and behaviors, today announced that it has raised $30 million in new funding. BNP Paribas led the round and Angel Rodriguez-Issa, Global Head of Strategic Investments, Global Markets at BNP Paribas, has joined Digital Reasoning’s board of directors.
The Partnership Fund made an additional investment in Digital Reasoning as part of this round.
“The Partnership for New York City represents the city’s business leaders and largest private sector employers. We work together with government, labor and the nonprofit sector to promote economic growth and job creation in New York.
Cross Hudson access is a critical issue for the New York City business community. Half of the jobs in the city are at companies with more than 500 employees. Virtually all these large companies have business operations and employees who live on both sides of the Hudson River. Based on our analysis, every hour delay on New Jersey Transit costs New York business $5.9 million. The economic consequences of a failure in the 100 year old tunnels would be enormous for both the affected businesses and for our entire region.
The recurring delays and problems with current cross-Hudson access are evidence the North River Tunnels cannot handle the 100 percent ridership increase that is expected by 2040. This is a national issue because our region generates 9 percent of the economic output for the entire country. The Hudson tunnels connect the nation’s most important financial and commercial center with the rest of America.
The elected leadership of New York and New Jersey, our Congressional delegations, transit advocates and business leaders are committed to doing everything in their powers to move the Gateway project forward. Hopefully, the White House and Congress will agree to a new national infrastructure initiative that is aggressive enough to fund critical projects, including Gateway. We are prepared to mobilize the expertise and private capital needed to launch a national rebuilding program, assuming the White House and Congress can agree on its terms. This is clearly a necessity for America’s future as a global economic power and should be the top priority of the federal government in 2018.”
“After nearly a decade of growth for the fintech sector, it has taken a foothold in financial services. The ability to quickly adopt external innovation is creating competitive advantages for financial services companies. Entrepreneurial fintechs decreasingly see themselves as competitors with large financial institutions, but rather as partners in a large, highly regulated marketplace. Financial institutions and entrepreneurs all stand to benefit if they get the interaction right. The fast pace of technology advancement only underscores the importance of getting fintech adoption right.
It is also apparent, however, that collaboration between financial institutions and fintechs remains a challenging and time-consuming process. Tactical hurdles are slowing smooth and efficient technology adoption by established financial service providers. The questions are: Why? What’s occurring? And what can be done to increase alignment to realize mutual benefits?
To learn the answers, the fintech innovation lab took advantage of its unique window into both the major financial companies who serve as Lab sponsors and the entrepreneurs who have gone through the mentoring program.
On February 26, 2018, Kathryn Wylde, President and CEO of the Partnership for New York City, testified to the New York City Council on the impact of the federal tax law on New York City. Below is a summary of her comments.
“As the nation’s business and real estate capital, New York City can expect to benefit from federal tax reform, particularly the reduction of corporate tax rates and of taxes on repatriation of profits from overseas operations. Many corporations have already announced plans to dedicate a portion of tax savings to salary increases for lower wage employees, additional employee bonuses and expanded investment in the U.S. But not all businesses are realizing equal benefits. For example, partnerships like legal and accounting firms and boutique investment banks and venture capital firms—all major employers in the city—are not getting the tax advantages of so-called pass-through entities under the new law. And many implications of the law are still not fully understood.
The biggest negative impact for the city is the loss of state and local tax deductibility for individual taxpayers, specifically capping those deductions at $10,000. As a result, residents of New York and nine other states with high property and personal income taxes will not see the same tax reductions as tax filers in lower tax states. On the contrary, some highly compensated New York employees — think Wall Street, corporate executives, tech entrepreneurs, entertainers, hospital administrators and doctors—will see a tax increase.
Contrary to some political rhetoric, the Trump tax reform is probably going to lower the taxes of most low- and middle-income households, although not as much here in New York as in other states. Our Partnership analysis shows that the typical New York single taxpayer earning more than $500,000 and married taxpayer earning more than $750,000 will have a bigger tax obligation because of the inability to deduct state and local income and property taxes.
There are about 60,000 tax filers who earn over $1 million in the state, most of whom will be paying between 52 and 57 percent of their marginal income to the government, with the highest tax burden falling on residents of New York City and its suburbs.
The taxpayers our city and state rely on for most of their revenues are severely impacted. The top one percent of tax filers—city residents who earn more than $700,000—account for 49 percent of all city income tax revenues and also generate significant economic activity through their spending power. These are 37,200 households out of 3.7 million total income tax filers.
There is also a competitiveness issue. New York residents whose taxes are not actually increasing under the new law—due to lower rates, the child tax credit, and higher standard deduction—will still fare worse than residents of most other states. An average family of four earning $175,000 will pay 25 percent of their income in taxes in New York, but only 14 percent if they reside in Florida. For the family earning $750,000, 40 percent of their income will be spent on taxes in New York versus 30 percent in Florida.
So the federal tax law will help our businesses compete in global markets, but it will make it more difficult and more expensive for them to recruit and retain top talent. Employers in key industries are calculating how to respond to this challenge— should they increase compensation to offset the tax burden, or should they relocate jobs to London, Asia, or lower-taxed American cities? In short, New York will be the global commercial center with the highest income tax rates in the world on its top earners. This will make it more expensive for employers to attract talent to the city and for entrepreneurs to build businesses here.
It is important that leaders in city and state government demonstrate their understanding of these issues. Governor Cuomo has included measures in his executive budget that attempt to offer some relief to those who will be most impacted by personal income tax increases. This is the right message to send to employers and taxpayers. On the other hand, proposals coming out of some quarters for another millionaire’s tax or other tax increases on high earners put the city and state in jeopardy of significant revenue and job losses. Anyone who thinks migration of jobs and high earners out of the city isn’t happening should speak to the realtors in Florida.
Elected officials around the country and world have quickly understood the competitive opportunity for poaching jobs and talent from New York. We urge the City Council and other elected officials to help fend off these efforts, first by acknowledging that we have a problem and second by looking at the current structure of the UBT and other tax laws and regulations to ensure that the city is taking whatever measures it can to mitigate the negative impact of the federal law on individuals and certain pass-through entities. We do not project that this tax law is a net negative for New York’s economy, unless we fail to deal honestly with its implications. We appreciate this Council hearing as an illustration of the kind of fact-finding and policy review that is necessary to keep New York competitive.”